What the manual says
Manufacturer manualTHERMAL FUSE LOCKOUT
What causes this fault?
This fault occurs when the internal temperature inside the main heat exchanger has reached an extreme, dangerous limit, causing a one-time safety fuse to blow. The root cause is typically a severe lack of water flow or a significant build-up of debris and limescale that has caused the component to dry-fire and get too hot. Because the fuse is designed to break permanently to protect your home, the boiler cannot be restarted simply by pressing a button.
Engineer required
This is a high severity fault. Stop using the boiler and call a Gas Safe registered engineer. Do not attempt gas-related repairs yourself.
Avoid the next call-out bill
A cover plan would handle faults like 4.5: no call-out fees, no surprise bills.
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